[HTML][HTML] Docosahexaenoic acid accumulates in cardiolipin and enhances HT-29 cell oxidant production
SM Watkins, LC Carter, JB German - Journal of lipid research, 1998 - ASBMB
The objective of this study was to investigate membrane fatty acids for their effects on
mitochondrial function in live cells. Mitochondrial potential and oxidant production were
measured in human colonic adenocarcinoma (HT-29) cells with membranes enhanced in
either oleic acid, linoleic acid, arachidonic acid, eicosapentaenoic acid, or docosahexaenoic
acid. Docosahexaenoic acid-enriched cells had increased mitochondrial potential and
produced 5-fold more cellular oxidants than did cells enriched with any other fatty acid …
mitochondrial function in live cells. Mitochondrial potential and oxidant production were
measured in human colonic adenocarcinoma (HT-29) cells with membranes enhanced in
either oleic acid, linoleic acid, arachidonic acid, eicosapentaenoic acid, or docosahexaenoic
acid. Docosahexaenoic acid-enriched cells had increased mitochondrial potential and
produced 5-fold more cellular oxidants than did cells enriched with any other fatty acid …