Cellular damage induced by reactive oxygen species (ROS) in normal tissues has been
implicated in the etiology of several human ailments. Among the subcellular organelles,
damage to mitochondria is considered crucial and can lead to cytotoxicity and cell death.
However, the same damage, if it is selectively induced in cancer tissues can lead to its cure.
Hence analyzing the mechanisms of such damage and its modulation may result in better
prevention or cure. Using mitochondria derived from rat brain/liver as well as sarcoma 180 …