Megestrol acetate for treatment of anorexia‐cachexia syndrome
VR Garcia, E López‐Briz, RC Sanchis… - Cochrane Database …, 2013 - cochranelibrary.com
VR Garcia, E López‐Briz, RC Sanchis, JLG Perales, S Bort‐Martí
Cochrane Database of Systematic Reviews, 2013•cochranelibrary.comBackground This is an updated version of a previously published review in The Cochrane
Library (2005, Issue 2) on'Megestrol acetate for the treatment of anorexia‐cachexia
syndrome'. Megestrol acetate (MA) is currently used to improve appetite and to increase
weight in cancer‐associated anorexia. In 1993, MA was approved by the US Food and Drug
Administration for the treatment of anorexia, cachexia or unexplained weight loss in patients
with AIDS. The mechanism by which MA increases appetite is unknown and its effectiveness …
Library (2005, Issue 2) on'Megestrol acetate for the treatment of anorexia‐cachexia
syndrome'. Megestrol acetate (MA) is currently used to improve appetite and to increase
weight in cancer‐associated anorexia. In 1993, MA was approved by the US Food and Drug
Administration for the treatment of anorexia, cachexia or unexplained weight loss in patients
with AIDS. The mechanism by which MA increases appetite is unknown and its effectiveness …
Background
This is an updated version of a previously published review in The Cochrane Library (2005, Issue 2) on'Megestrol acetate for the treatment of anorexia‐cachexia syndrome'. Megestrol acetate (MA) is currently used to improve appetite and to increase weight in cancer‐associated anorexia. In 1993, MA was approved by the US Food and Drug Administration for the treatment of anorexia, cachexia or unexplained weight loss in patients with AIDS. The mechanism by which MA increases appetite is unknown and its effectiveness for anorexia and cachexia in neoplastic and AIDS (acquired immunodeficiency syndrome) patients is under investigation.
Objectives
To evaluate the efficacy, effectiveness and safety of MA in palliating anorexia‐cachexia syndrome in patients with cancer, AIDS and other underlying pathologies.
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