[HTML][HTML] Monogenic diabetes in overweight and obese youth diagnosed with type 2 diabetes: the TODAY clinical trial

JW Kleinberger, KC Copeland, RG Gandica… - Genetics in …, 2018 - Elsevier
Purpose Monogenic diabetes accounts for 1–2% of diabetes cases. It is often undiagnosed,
which may lead to inappropriate treatment. This study was performed to estimate the
prevalence of monogenic diabetes in a cohort of overweight/obese adolescents diagnosed
with type 2 diabetes (T2D). Methods Sequencing using a custom monogenic diabetes gene
panel was performed on a racially/ethnically diverse cohort of 488 overweight/obese
adolescents with T2D in the Treatment Options for Type 2 Diabetes in Adolescents and …