[HTML][HTML] Glutamate as a neurotransmitter in the brain: review of physiology and pathology
BS Meldrum - The Journal of nutrition, 2000 - Elsevier
Glutamate is the principal excitatory neurotransmitter in brain. Our knowledge of the
glutamatergic synapse has advanced enormously in the last 10 years, primarily through
application of molecular biological techniques to the study of glutamate receptors and
transporters. There are three families of ionotropic receptors with intrinsic cation permeable
channels [N-methyl-D-aspartate (NMDA), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic
acid (AMPA) and kainate]. There are three groups of metabotropic, G protein–coupled …
glutamatergic synapse has advanced enormously in the last 10 years, primarily through
application of molecular biological techniques to the study of glutamate receptors and
transporters. There are three families of ionotropic receptors with intrinsic cation permeable
channels [N-methyl-D-aspartate (NMDA), α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic
acid (AMPA) and kainate]. There are three groups of metabotropic, G protein–coupled …