Experimental and mathematical approaches to quantify recirculation kinetics of lymphocytes
VV Ganusov, M Tomura - Mathematical, Computational and Experimental …, 2021 - Springer
VV Ganusov, M Tomura
Mathematical, Computational and Experimental T Cell Immunology, 2021•SpringerThe adaptive immune system of mammals includes two major subsets of lymphocytes, B and
T lymphocytes [1, 2]. One of the major functions of the adaptive immune system is to protect
its host from invading microorganisms such as viruses and bacteria. Because microbes can
enter the host from multiple areas such as via skin, lung, or gut mucosa, there is a need to
have lymphocytes present near these tissues. In addition, because every lymphocyte is, in
general, specific to only one microbial determinant and there are many microbial …
T lymphocytes [1, 2]. One of the major functions of the adaptive immune system is to protect
its host from invading microorganisms such as viruses and bacteria. Because microbes can
enter the host from multiple areas such as via skin, lung, or gut mucosa, there is a need to
have lymphocytes present near these tissues. In addition, because every lymphocyte is, in
general, specific to only one microbial determinant and there are many microbial …
Abstract
The adaptive immune system of mammals includes two major subsets of lymphocytes, B and T lymphocytes [1, 2]. One of the major functions of the adaptive immune system is to protect its host from invading microorganisms such as viruses and bacteria. Because microbes can enter the host from multiple areas such as via skin, lung, or gut mucosa, there is a need to have lymphocytes present near these tissues. In addition, because every lymphocyte is, in general, specific to only one microbial determinant and there are many microbial determinants, only a small percent of lymphocytes would be able to recognize any specific microbe.
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