GDNF is abundant in the adult rat gut
RJ Peters, MA Osinski, JA Hongo, GL Bennett… - Journal of the autonomic …, 1998 - Elsevier
Glial derived neurotrophic factor (GDNF) is essential for the development of the enteric
nervous system (ENS). Although previous work has measured GDNF mRNA levels, little is
known about the concentration of GDNF protein produced in developing or adult tissues.
The aim of this study was to quantitate the concentration of GDNF protein in various tissues
of the developing and adult rat and in adult human gut. A two site antibody immunoassay
was used to quantitate GDNF using recombinant rat GDNF as a standard. In the adult rat …
nervous system (ENS). Although previous work has measured GDNF mRNA levels, little is
known about the concentration of GDNF protein produced in developing or adult tissues.
The aim of this study was to quantitate the concentration of GDNF protein in various tissues
of the developing and adult rat and in adult human gut. A two site antibody immunoassay
was used to quantitate GDNF using recombinant rat GDNF as a standard. In the adult rat …