AIM: Clopidogrel is a widely used anti-thrombotic for the prevention of stent thrombosis and
cardiovascular events in patients with coronary atherosclerosis. Clopidogrel has been
shown to exhibit anti-inflammatory effects that are related to the attenuated activation of
platelets. Atherosclerosis is a complex process in which the immune system and the
endothelium appear to play a prominent role. Herein, we tested the hypothesis that
clopidogrel will influence plaque size and composition in the atherosclerosis prone …