[HTML][HTML] Phospholipase Cγ2 (PLCγ2) is key component in Dectin-2 signaling pathway, mediating anti-fungal innate immune responses
C-type lectin receptors (CLRs) such as Dectin-2 function as pattern recognition receptors to
sense fungal infection. However, the signaling pathways induced by these receptors remain
largely unknown. Previous studies suggest that the CLR-induced signaling pathway may
utilize similar signaling components as the B cell receptor-induced signaling pathway.
Phospholipase Cγ2 (PLCγ2) is a key component in B cell receptor signaling, but its role in
other signaling pathways has not been fully characterized. Here, we show that PLCγ2 …
sense fungal infection. However, the signaling pathways induced by these receptors remain
largely unknown. Previous studies suggest that the CLR-induced signaling pathway may
utilize similar signaling components as the B cell receptor-induced signaling pathway.
Phospholipase Cγ2 (PLCγ2) is a key component in B cell receptor signaling, but its role in
other signaling pathways has not been fully characterized. Here, we show that PLCγ2 …