SIRT1 expression is associated with poor prognosis of diffuse large B-cell lymphoma
Abstract Sirtuin1 (SIRT1) is a nicotinamide adenine dinucleotide-dependent deacetylase.
Recently, it is suggested that SIRT1 may be involved in the development of malignant
tumors including mouse lymphoma. Therefore, we investigated the prevalence and the
prognostic impact of SIRT1 expression in diffuse large B-cell lymphoma (DLBCL).
Immunohistochemical expression of SIRT1, p53, bcl2, CD10, bcl6, and multiple myeloma-1
(MUM1) were evaluated by using a 2 mm core from 104 DLBCL patients for tissue …
Recently, it is suggested that SIRT1 may be involved in the development of malignant
tumors including mouse lymphoma. Therefore, we investigated the prevalence and the
prognostic impact of SIRT1 expression in diffuse large B-cell lymphoma (DLBCL).
Immunohistochemical expression of SIRT1, p53, bcl2, CD10, bcl6, and multiple myeloma-1
(MUM1) were evaluated by using a 2 mm core from 104 DLBCL patients for tissue …