The Reactome pathway knowledgebase

D Croft, AF Mundo, R Haw, M Milacic… - Nucleic acids …, 2014 - academic.oup.com
D Croft, AF Mundo, R Haw, M Milacic, J Weiser, G Wu, M Caudy, P Garapati, M Gillespie
Nucleic acids research, 2014academic.oup.com
Abstract Reactome (http://www. reactome. org) is a manually curated open-source open-
data resource of human pathways and reactions. The current version 46 describes 7088
human proteins (34% of the predicted human proteome), participating in 6744 reactions
based on data extracted from 15 107 research publications with PubMed links. The
Reactome Web site and analysis tool set have been completely redesigned to increase
speed, flexibility and user friendliness. The data model has been extended to support …
Abstract
Reactome (http://www.reactome.org) is a manually curated open-source open-data resource of human pathways and reactions. The current version 46 describes 7088 human proteins (34% of the predicted human proteome), participating in 6744 reactions based on data extracted from 15 107 research publications with PubMed links. The Reactome Web site and analysis tool set have been completely redesigned to increase speed, flexibility and user friendliness. The data model has been extended to support annotation of disease processes due to infectious agents and to mutation.
Oxford University Press