Genetic errors of the human caspase recruitment domain–B-cell lymphoma 10–mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex …
RP de Diego, S Sánchez-Ramón… - Journal of Allergy and …, 2015 - Elsevier
Three members of the caspase recruitment domain (CARD) family of adaptors (CARD9,
CARD10, and CARD11) are known to form heterotrimers with B-cell lymphoma 10 (BCL10)
and mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (MALT1). These 3
CARD-BCL10-MALT1 (CBM) complexes activate nuclear factor κB in both the innate and
adaptive arms of immunity. Human inherited defects of the 3 components of the CBM
complex, including the 2 adaptors CARD9 and CARD11 and the 2 core components BCL10 …
CARD10, and CARD11) are known to form heterotrimers with B-cell lymphoma 10 (BCL10)
and mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (MALT1). These 3
CARD-BCL10-MALT1 (CBM) complexes activate nuclear factor κB in both the innate and
adaptive arms of immunity. Human inherited defects of the 3 components of the CBM
complex, including the 2 adaptors CARD9 and CARD11 and the 2 core components BCL10 …