[HTML][HTML] Transforming Growth Factor β Up-regulates Expression of the N-Acetylglucosaminyltransferase V Gene in Mouse Melanoma Cells (∗)
E Miyoshi, A Nishikawa, Y Ihara, H Saito… - Journal of Biological …, 1995 - ASBMB
β-1, 6-N-acetylglucosaminyltransferase V (GnT-V)(EC 2.4. 1.155) that catalyzes β-1, 6
branching in asparagine-linked oligosaccharides is activated on viral or oncogenic
transformation and is associated with tumor metastasis. To study the molecular mechanisms
involved in regulation of expression of the GnT-V gene, we cloned cDNA and genomic DNA
for the enzyme (Saito, H., Nishikawa, A., Gu, J., Ihara, Y., Soejima, Y., Sekiya, C., Niikawa,
N., and Taniguchi, N.(1994) Biochem. Biophys. Res. Commun. 198, 318-327). We found that …
branching in asparagine-linked oligosaccharides is activated on viral or oncogenic
transformation and is associated with tumor metastasis. To study the molecular mechanisms
involved in regulation of expression of the GnT-V gene, we cloned cDNA and genomic DNA
for the enzyme (Saito, H., Nishikawa, A., Gu, J., Ihara, Y., Soejima, Y., Sekiya, C., Niikawa,
N., and Taniguchi, N.(1994) Biochem. Biophys. Res. Commun. 198, 318-327). We found that …