Glyoxylate synthesis, and its modulation and influence on oxalate synthesis

RP HOLMES, DG ASSIMOS - The Journal of urology, 1998 - Elsevier
PURPOSE: We define the major pathways of hepatic oxalate synthesis in humans, examine
the association with other metabolic pathways and identify ways that oxalate synthesis may
be modified. In addition, we suggest what is required for further progress in this area.
MATERIALS AND METHODS: We consolidated relevant data primarily from recently
published literature, considered new pharmacological approaches to decrease oxalate
synthesis, and formulated an overview of the regulation and modification of oxalate …