[HTML][HTML] Endogenous memory CD8 T cells directly mediate cardiac allograft rejection

CA Su, S Iida, T Abe, RL Fairchild - American journal of transplantation, 2014 - Elsevier
Differences in levels of environmentally induced memory T cells that cross-react with donor
MHC molecules are postulated to account for the efficacy of allograft tolerance-inducing
strategies in rodents versus their failure in nonhuman primates and human transplant
patients. Strategies to study the impact of donor-reactive memory T cells on allografts in
rodents have relied on the pretransplant induction of memory T cells cross-reactive with
donor allogeneic MHC molecules through recipient viral infection, priming directly with …