Metformin has a positive therapeutic effect on prostate cancer in patients with type 2 diabetes mellitus

RW Chong, V Vasudevan, J Zuber… - The American journal of the …, 2016 - Elsevier
Objective Prostate cancer and type 2 diabetes mellitus (DM2) are both common diseases
found in the elderly male population. The diabetic drug, metformin, has been shown to have
antineoplastic properties and demonstrated better treatment outcomes when used as
adjuvant therapy in patients with breast cancer. The hormonally-sensitive cancer analogous
to breast cancer in men is prostate cancer. We investigated improved survival, lower risks of
recurrences, and lower, more stable levels of prostate-specific antigen (PSA) in patients with …