Isolated systolic hypertension, pulse pressure, and arterial stiffness as risk factors for cardiovascular disease

MF O'Rourke - Current hypertension reports, 1999 - Springer
MF O'Rourke
Current hypertension reports, 1999Springer
Arterial stiffening with age is responsible for isolated systolic hypertension, for elevation of
systolic pressure with age, and for the majority of cardiovascular events in the elderly,
especially left ventricular failure. Change in brachial pulse pressure with age
underestimates change in aortic pulse pressure; change with vasodilator agents, especially
nitrates, underestimates beneficial effects of these agents on the heart. New methods based
on pulse wave analysis complement sphygmomanometry in assessing ill effects of aging …
Abstract
Arterial stiffening with age is responsible for isolated systolic hypertension, for elevation of systolic pressure with age, and for the majority of cardiovascular events in the elderly, especially left ventricular failure. Change in brachial pulse pressure with age underestimates change in aortic pulse pressure; change with vasodilator agents, especially nitrates, underestimates beneficial effects of these agents on the heart. New methods based on pulse wave analysis complement sphygmomanometry in assessing ill effects of aging and benefits of drug therapy for hypertension.
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