Comparison of intravenously administered methadone, morphine and heroin
DR Jasinski, KL Preston - Drug and alcohol dependence, 1986 - Elsevier
Data from previously reported studies suggest that methadone may be more euphorigenic
than other morphine-like drugs. To determine whether methadone is more potent in
producing euphoria relative to its other opiate-like effects, single doses of intravenously
administered methadone, morphine, heroin and placebo were compared in non-dependent
post-addict volunteers. Morphine-like physiologic, subjective and behavioral effects were
measured periodically for 24 h after drug administration. Under the conditions of the …
than other morphine-like drugs. To determine whether methadone is more potent in
producing euphoria relative to its other opiate-like effects, single doses of intravenously
administered methadone, morphine, heroin and placebo were compared in non-dependent
post-addict volunteers. Morphine-like physiologic, subjective and behavioral effects were
measured periodically for 24 h after drug administration. Under the conditions of the …