Evaluation of patients with hepatocellular carcinomas that do not produce α-fetoprotein
VG Agopian, MP Harlander-Locke, D Markovic… - JAMA …, 2017 - jamanetwork.com
Importance Serum α-fetoprotein (AFP) is a biomarker for hepatocellular carcinomas (HCCs)
associated with a more aggressive tumor phenotype and inferior outcomes after a liver
transplant (LT). Data on the outcomes for patients with HCCs that do not produce AFP are
limited. Objective To compare characteristics and outcomes among LT recipients with
radiographically apparent HCC lesions with AFP-producing tumors or with tumors that do
not produce AFP (hereafter referred to as non-AFP–producing tumors), and to identify factors …
associated with a more aggressive tumor phenotype and inferior outcomes after a liver
transplant (LT). Data on the outcomes for patients with HCCs that do not produce AFP are
limited. Objective To compare characteristics and outcomes among LT recipients with
radiographically apparent HCC lesions with AFP-producing tumors or with tumors that do
not produce AFP (hereafter referred to as non-AFP–producing tumors), and to identify factors …