Association between use of acid-suppressive medications and antibiotics during infancy and allergic diseases in early childhood

E Mitre, A Susi, LE Kropp, DJ Schwartz… - JAMA …, 2018 - jamanetwork.com
Importance Allergic diseases are prevalent in childhood. Early exposure to medications that
can alter the microbiome, including acid-suppressive medications and antibiotics, may
influence the likelihood of allergy. Objective To determine whether there is an association
between the use of acid-suppressive medications or antibiotics in the first 6 months of
infancy and development of allergic diseases in early childhood. Design, Setting, and
Participants A retrospective cohort study was conducted in 792 130 children who were …