Background Allergic sensitization to fungi has been associated with asthma severity. As a
result, it has been largely assumed that the contribution of fungi to allergic disease is
mediated through their potent antigenicity. Objective We sought to determine the mechanism
by which fungi affect asthma development and severity. Methods We integrated
epidemiologic and experimental asthma models to explore the effect of fungal exposure on
asthma development and severity. Results We report that fungal exposure enhances …