Predicting the atopic march: results from the Canadian healthy infant longitudinal development study

MM Tran, DL Lefebvre, C Dharma, D Dai… - Journal of Allergy and …, 2018 - Elsevier
Background The atopic march describes the progression from atopic dermatitis during
infancy to asthma and allergic rhinitis in later childhood. In a Canadian birth cohort we
investigated whether concomitant allergic sensitization enhances subsequent development
of these allergic diseases at age 3 years. Methods Children completed skin prick testing at
age 1 year. Children were considered sensitized if they produced a wheal 2 mm or larger
than that elicited by the negative control to any of 10 inhalant or food allergens. Children …