[HTML][HTML] The airway microbiome in patients with severe asthma: associations with disease features and severity

YJ Huang, S Nariya, JM Harris, SV Lynch… - Journal of Allergy and …, 2015 - Elsevier
Background Asthma is heterogeneous, and airway dysbiosis is associated with clinical
features in patients with mild-to-moderate asthma. Whether similar relationships exist among
patients with severe asthma is unknown. Objective We sought to evaluate relationships
between the bronchial microbiome and features of severe asthma. Methods Bronchial
brushings from 40 participants in the Bronchoscopic Exploratory Research Study of
Biomarkers in Corticosteroid-refractory Asthma (BOBCAT) study were evaluated by using …