Staphylococcus aureus α-toxin modulates skin host response to viral infection
L Bin, BE Kim, A Brauweiler, E Goleva, J Streib… - Journal of allergy and …, 2012 - Elsevier
BACKGROUND: Patients with atopic dermatitis (AD) with a history of eczema herpeticum
have increased staphylococcal colonization and infections. However, whether
Staphylococcus aureus alters the outcome of skin viral infection has not been determined.
OBJECTIVE: We investigated whether S aureus toxins modulated host response to herpes
simplex virus (HSV) 1 and vaccinia virus (VV) infections in normal human keratinocytes
(NHKs) and in murine infection models. METHODS: NHKs were treated with S aureus toxins …
have increased staphylococcal colonization and infections. However, whether
Staphylococcus aureus alters the outcome of skin viral infection has not been determined.
OBJECTIVE: We investigated whether S aureus toxins modulated host response to herpes
simplex virus (HSV) 1 and vaccinia virus (VV) infections in normal human keratinocytes
(NHKs) and in murine infection models. METHODS: NHKs were treated with S aureus toxins …
