[PDF][PDF] Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently prognostic in primary myelofibrosis: a comprehensive cytokine profiling study

A Tefferi, R Vaidya, D Caramazza, C Finke… - Journal of Clinical …, 2011 - researchgate.net
A Tefferi, R Vaidya, D Caramazza, C Finke, T Lasho, A Pardanani
Journal of Clinical Oncology, 2011researchgate.net
Purpose Abnormal cytokine expression accompanies myelofibrosis and might be a
therapeutic target for Janus-associated kinase (JAK) inhibitor drugs. This study describes
the spectrum of plasma cytokine abnormalities in primary myelofibrosis (PMF) and examines
their phenotypic correlates and prognostic significance.
Purpose
Abnormal cytokine expression accompanies myelofibrosis and might be a therapeutic target for Janus-associated kinase (JAK) inhibitor drugs. This study describes the spectrum of plasma cytokine abnormalities in primary myelofibrosis (PMF) and examines their phenotypic correlates and prognostic significance.
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