Long-term treatment with egg oral immunotherapy enhances sustained unresponsiveness that persists after cessation of therapy

SM Jones, AW Burks, C Keet, BP Vickery… - Journal of Allergy and …, 2016 - Elsevier
Background We previously reported the results of a randomized placebo-controlled study of
egg oral immunotherapy (eOIT) in which 27.5% of subjects achieved sustained
unresponsiveness (SU) after 2 years. Here we report the results of treatment through 4 years
and long-term follow-up. Objective We sought to evaluate the efficacy and safety of eOIT in
participants treated up to 4 years. Methods Children with egg allergy (5-18 years old)
received eOIT (n= 40) for up to 4 years or placebo (n= 15) for 1 year or less. The key …