Investigations on CXCL13 in anti–N-methyl-D-aspartate receptor encephalitis: a potential biomarker of treatment response
F Leypoldt, R Höftberger, MJ Titulaer… - JAMA …, 2015 - jamanetwork.com
Importance Anti–N-methyl-D-aspartate receptor (NMDAR) encephalitis is a severe but
treatable autoimmune encephalitis affecting mainly young adults and children. The lack of
suitable biomarkers of disease activity makes treatment decisions and identification of
relapses challenging. Objective To determine the levels of the B-cell–attracting CXC motif
chemokine 13 (CXCL13) in serum samples and cerebrospinal fluid (CSF) of patients with
anti-NMDAR encephalitis and whether they can be used as biomarkers of treatment …
treatable autoimmune encephalitis affecting mainly young adults and children. The lack of
suitable biomarkers of disease activity makes treatment decisions and identification of
relapses challenging. Objective To determine the levels of the B-cell–attracting CXC motif
chemokine 13 (CXCL13) in serum samples and cerebrospinal fluid (CSF) of patients with
anti-NMDAR encephalitis and whether they can be used as biomarkers of treatment …