Seizures and encephalitis in myelin oligodendrocyte glycoprotein IgG disease vs aquaporin 4 IgG disease
SHM Hamid, D Whittam, M Saviour, A Alorainy… - JAMA …, 2018 - jamanetwork.com
Importance Antibodies to myelin oligodendrocyte glycoprotein IgG (MOG-IgG) are
increasingly detected in patients with non–multiple sclerosis–related demyelination, some of
whom manifest a neuromyelitis optica (NMO) phenotype. Cortical involvement,
encephalopathy, and seizures are rare in aquaporin 4 antibody (AQP4-IgG)–related NMO in
the white European population. However, the authors encountered several patients with
seizures associated with MOG-IgG disease. Objective To compare incidence of seizures and …
increasingly detected in patients with non–multiple sclerosis–related demyelination, some of
whom manifest a neuromyelitis optica (NMO) phenotype. Cortical involvement,
encephalopathy, and seizures are rare in aquaporin 4 antibody (AQP4-IgG)–related NMO in
the white European population. However, the authors encountered several patients with
seizures associated with MOG-IgG disease. Objective To compare incidence of seizures and …