Population-level evidence for an autoimmune etiology of epilepsy

MS Ong, IS Kohane, T Cai, MP Gorman… - JAMA …, 2014 - jamanetwork.com
Importance Epilepsy is a debilitating condition, often with neither a known etiology nor an
effective treatment. Autoimmune mechanisms have been increasingly identified. Objective
To conduct a population-level study investigating the relationship between epilepsy and
several common autoimmune diseases. Design, Setting, and Participants A retrospective
population-based study using claims from a nationwide employer-provided health insurance
plan in the United States. Participants were beneficiaries enrolled between 1999 and 2006 …