Intravenous immunoglobulin therapy for toxic shock syndrome

W Barry, L Hudgins, ST Donta, EL Pesanti - Jama, 1992 - jamanetwork.com
Staphylococcus aureusand group AStreptococcus pyogenesproduce toxic shock syndrome
characterized by hypotension and multisystem organ failure. While conventional therapy has
consisted of antibiotics and intensive supportive care, some experimental evidence
suggests that immunoglobulins directed against the toxins may be effective additional
therapy. We report a case of" toxic strep syndrome" in which intravenous immunoglobulin
was administered when signs and symptoms were worsening while the patient was …