Plasma membrane recycling is an important process necessary for maintaining membrane
composition. The motor protein myosin Vb regulates plasma membrane recycling through its
association with Rab11a. Overexpression of the tail of myosin Vb disrupts trafficking out of
plasma membrane recycling systems and leads to the accumulation of Rab11a in both
polarized and non-polarized cells. We have investigated the association of Rab11 family
interacting protein 2 (Rab11-FIP2) with myosin Vb as an adapter protein between Rab11a …