[HTML][HTML] Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission

N Taguchi, N Ishihara, A Jofuku, T Oka… - Journal of Biological …, 2007 - ASBMB
Organelles are inherited to daughter cells beyond dynamic changes of the membrane
structure during mitosis. Mitochondria are dynamic entities, frequently dividing and fusing
with each other, during which dynamin-related GTPase Drp1 is required for the fission
reaction. In this study, we analyzed mitochondrial dynamics in mitotic mammalian cells.
Although mitochondria in interphase HeLa cells are long tubular network structures, they are
fragmented in early mitotic phase, and the filamentous network structures are subsequently …