Is the high propensity of ethanolamine plasmalogens to form non-lamellar lipid structures manifested in the properties of biomembranes?
K Lohner - Chemistry and physics of lipids, 1996 - Elsevier
Plasmalogens are glycerophospholipids characterized by an alk-1′-enylether bond in
position sn-1 and an acyl bond in position sn-2. These ubiquitous etherlipids exhibit a
different molecular structure as compared to diacyl phospholipids. The most peculiar change
is a perpendicular orientation of the sn-2 acyl chain at all segments to the membrane
surface. This extended conformation results in an effectively longer aliphatic chain in
plasmalogen than in the diacyl analog. Moreover, the lack of the carbonyl oxygen in position …
position sn-1 and an acyl bond in position sn-2. These ubiquitous etherlipids exhibit a
different molecular structure as compared to diacyl phospholipids. The most peculiar change
is a perpendicular orientation of the sn-2 acyl chain at all segments to the membrane
surface. This extended conformation results in an effectively longer aliphatic chain in
plasmalogen than in the diacyl analog. Moreover, the lack of the carbonyl oxygen in position …