PTEN hamartoma of soft tissue: a distinctive lesion in PTEN syndromes

KC Kurek, E Howard, LB Tennant, J Upton… - The American journal …, 2012 - journals.lww.com
PTEN hamartoma tumor syndrome (PHTS) presents in a spectrum that encompasses the
eponymous disorders Cowden and Bannayan-Riley-Ruvalcaba. Herein, we delineate the
distinctive histopathology of a predominantly intramuscular lesion in PHTS, often called
“arteriovenous malformation,” because of certain imaging and histopathologic features.
Cases were identified by review of lesions resected from patients with PHTS registered at
our Vascular Anomalies Center and of unusual intramuscular vascular anomalies in our …