Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling …
The placenta plays an important role as a regulator of fetal nutrition and growth throughout
development and placental factors contribute to gestational abnormalities such as
preeclampsia. This study describes the genome-wide gene expression profiles of a large
(n= 60) set of human placentas in order to uncover gene expression patterns associated
with preeclampsia. In addition to confirming changes in expression of soluble factors
associated with preeclampsia such as sFLT1 (soluble fms-like tyrosine kinase-1), sENG …
development and placental factors contribute to gestational abnormalities such as
preeclampsia. This study describes the genome-wide gene expression profiles of a large
(n= 60) set of human placentas in order to uncover gene expression patterns associated
with preeclampsia. In addition to confirming changes in expression of soluble factors
associated with preeclampsia such as sFLT1 (soluble fms-like tyrosine kinase-1), sENG …