Association between myeloperoxidase levels and risk of coronary artery disease

R Zhang, ML Brennan, X Fu, RJ Aviles, GL Pearce… - Jama, 2001 - jamanetwork.com
ContextMyeloperoxidase (MPO), a leukocyte enzyme that promotes oxidation of lipoproteins
in atheroma, has been proposed as a possible mediator of atherosclerosis. ObjectiveTo
determine the association between MPO levels and prevalence of coronary artery disease
(CAD). Design, Setting, and PatientsCase-control study conducted from July to September
2000 in a US tertiary care referral center, including 158 patients with established CAD
(cases) and 175 patients without angiographically significant CAD (controls). Main Outcome …