Modulation of cytokine production by intravenous immunoglobulin in patients with enterovirus 71-associated brainstem encephalitis

SM Wang, HY Lei, MC Huang, LY Su, HC Lin… - Journal of clinical …, 2006 - Elsevier
BACKGROUND: Several epidemics of enterovirus 71 (EV71) infections occurred in Taiwan
since 1998. OBJECTIVES: We performed the study to determine the changes in cytokine
profiles associated with administration of intravenous immunoglobulin (IVIG) in patients with
EV71-associated brainstem encephalitis complicated by autonomic nervous system (ANS)
dysfunction and pulmonary edema. STUDY DESIGN: Plasma cytokine concentrations (IL-1β,
IL-6, IL-8, IFN-γ, TNF-α, IL-2, IL-4, IL-5, IL-10, and IL-13) were monitored on admission and …