Expression of p63 in potentially malignant and malignant oral lesions

A Sinha, S Chandra, V Raj, I Zaidi, S Saxena… - Journal of oral biology …, 2015 - Elsevier
Background p63, a member of p53 family, known to be expressed in embryonic tissues and
basal regenerative layers of many epithelial tissues in the adult, is also expressed in various
benign and malignant lesions of body including lesions of oral cavity. To evaluate the
expression of p63 and compare the expression qualitatively and quantitatively in normal
buccal mucosa, epithelial dysplasia, oral submucous fibrosis (OSMF), and oral squamous
cell carcinoma (OSCC). Methods The study material consisted of 45 archival cases which …