Left ventricular hypertrophy: pathogenesis, detection, and prognosis
BH Lorell, BA Carabello - Circulation, 2000 - Am Heart Assoc
BH Lorell, BA Carabello
Circulation, 2000•Am Heart Associncrease in ratio of angiotensin II AT2 to AT1 receptor subtypes). Some of these switches,
such as the increased expression of the slow myosin ATPase isoform-myosin heavy chain
relative to the fast myosin ATPase isoform-myosin heavy chain, are adaptive and promote a
more favorable myoenergetic economy. However, the long-term functional implications of
many of the changes in gene expression are still unclear in the context of integrated
cardiovascular function in vivo.
such as the increased expression of the slow myosin ATPase isoform-myosin heavy chain
relative to the fast myosin ATPase isoform-myosin heavy chain, are adaptive and promote a
more favorable myoenergetic economy. However, the long-term functional implications of
many of the changes in gene expression are still unclear in the context of integrated
cardiovascular function in vivo.
increase in ratio of angiotensin II AT2 to AT1 receptor subtypes). Some of these switches, such as the increased expression of the slow myosin ATPase isoform-myosin heavy chain relative to the fast myosin ATPase isoform-myosin heavy chain, are adaptive and promote a more favorable myoenergetic economy. However, the long-term functional implications of many of the changes in gene expression are still unclear in the context of integrated cardiovascular function in vivo.
Am Heart Assoc