[HTML][HTML] Left ventricular end-diastolic volume is normal in patients with heart failure and a normal ejection fraction: a renewed consensus in diastolic heart failure

MR Zile, MM LeWinter - Journal of the American College of Cardiology, 2007 - jacc.org
MR Zile, MM LeWinter
Journal of the American College of Cardiology, 2007jacc.org
The study published in this issue of the Journal by Maurer et al.(1) provides data which,
interpreted in the context of a number of recently published studies (2–8), allow us to
conclude that: 1) left ventricular (LV) end-diastolic volume (EDV) is normal in the vast
majority of patients with heart failure (HF) and a normal ejection fraction (HFNEF)(ie,
diastolic heart failure [DHF]); 2) the pathophysiology underlying the vast majority of patients
with HFNEF (DHF) primarily reflects the development of progressive diastolic dysfunction.
The study published in this issue of the Journal by Maurer et al.(1) provides data which, interpreted in the context of a number of recently published studies (2–8), allow us to conclude that: 1) left ventricular (LV) end-diastolic volume (EDV) is normal in the vast majority of patients with heart failure (HF) and a normal ejection fraction (HFNEF)(ie, diastolic heart failure [DHF]); 2) the pathophysiology underlying the vast majority of patients with HFNEF (DHF) primarily reflects the development of progressive diastolic dysfunction.
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