The pathology of human West Nile virus infection
BA Sampson, C Ambrosi, A Charlot, K Reiber… - Human pathology, 2000 - Elsevier
West Nile Virus (WNV) was identified by immunohistochemistry (IHC) and polymerase chain
reaction (PCR) as the etiologic agent in 4 encephalitis fatalities in New York City in the late
summer of 1999. The fatalities occurred in persons with a mean age of 81.5 years, each of
whom had underlying medical problems. Cardinal clinical manifestations included fever and
profound muscle weakness. Autopsy disclosed encephalitis in 2 instances and
meningoencephalitis in the remaining 2. The inflammation was mostly mononuclear and …
reaction (PCR) as the etiologic agent in 4 encephalitis fatalities in New York City in the late
summer of 1999. The fatalities occurred in persons with a mean age of 81.5 years, each of
whom had underlying medical problems. Cardinal clinical manifestations included fever and
profound muscle weakness. Autopsy disclosed encephalitis in 2 instances and
meningoencephalitis in the remaining 2. The inflammation was mostly mononuclear and …