[HTML][HTML] Diversity of globin function: enzymatic, transport, storage, and sensing
SN Vinogradov, L Moens - Journal of Biological Chemistry, 2008 - ASBMB
The availability of genomic information from the three kingdoms of life has altered
substantially our view of the globin superfamily. It is now evident that Hbs, 2 defined as
hemeproteins comprising five to eight α-helices (A–H), with an invariant His at position F8
providing the proximal ligand to the heme iron, occur as three families in two structural
classes (1). Within each family, the Hb can be either chimeric or SD. Historically, the first
members of the two families that display the canonical 3/3 α-helical fold were chimeric: the …
substantially our view of the globin superfamily. It is now evident that Hbs, 2 defined as
hemeproteins comprising five to eight α-helices (A–H), with an invariant His at position F8
providing the proximal ligand to the heme iron, occur as three families in two structural
classes (1). Within each family, the Hb can be either chimeric or SD. Historically, the first
members of the two families that display the canonical 3/3 α-helical fold were chimeric: the …