Maternal circulating angiogenic factors in twin and singleton pregnancies

JM Faupel-Badger, TF McElrath, M Lauria… - American journal of …, 2015 - Elsevier
Objective The purpose of this study was to compare longitudinally sampled maternal
angiogenic proteins between singleton and twin pregnancies. Study Design Placental
growth factor (PlGF), soluble feline McDonough sarcoma (fms)-like tyrosine kinase (sFlt)-1,
and soluble endoglin from healthy pregnant women were quantified at 10, 18, 26, and 35
weeks' gestation (n= 91), and during the third trimester (31-39 weeks) and at delivery (33-41
weeks; n= 41). Geometric means and 95% confidence intervals were calculated for …