Comparison of immune cell recruitment and function in endometrium during development of epitheliochorial (pig) and hemochorial (mouse and human) placentas

BA Croy, J Wessels, N Linton, C Tayade - Placenta, 2009 - Elsevier
The role of maternal immune cells in early implantation sites has received special attention
from reproductive biologists because immune cells participate in tissue transplant rejection.
During normal pregnancy, endometrial immune cells differ from those in blood by subset
distribution and appear to be activated but non-destructive of conceptuses. The immune
system evolved well before placental mammals. By comparing the regulation and functions
of endometrial immune cells between species in two phylogenetic clades that model …