Maternal–fetal HLA sharing and preeclampsia: variation in effects by seminal fluid exposure in a case–control study of nulliparous women in Iowa

EW Triche, KK Harland, EH Field… - Journal of reproductive …, 2014 - Elsevier
Whereas histocompatibility is critical for transplantation, HLA histo in compatibility is
associated with successful pregnancy. Literature on HLA sharing and preeclampsia has
been inconsistent; most studies focused on maternal–paternal rather than maternal–fetal
sharing. This study examines whether maternal–fetal histocompatibility is associated with
preeclampsia, and whether effects vary by semen exposure history. This case–control study
of nulliparous women was designed to examine associations among HLA sharing, semen …