Assessment of sperm antigen specific T regulatory cells in women with recurrent miscarriage

C Liu, XZ Wang, XB Sun - Early human development, 2013 - Elsevier
BACKGROUND AND AIMS: The prevalence of recurrent miscarriage (RM) is about 1–3% of
women; the pathogenesis of RM is not fully understood yet. This study aims to assess the
sperm antigen specific regulatory T cells (Treg) in women with RM. METHODS: A group of
women with RM was recruited into this study. The sperm antigen was extracted from the
semen samples of each woman's husband. The sperm antigen specific T cell response was
assessed by flow cytometry. RESULTS: Low frequency of sperm specific Tregs and high …