[HTML][HTML] Established cell lines used in cystic fibrosis research
DC Gruenert, M Willems, JJ Cassiman… - Journal of Cystic …, 2004 - Elsevier
DC Gruenert, M Willems, JJ Cassiman, RA Frizzell
Journal of Cystic Fibrosis, 2004•ElsevierThe development of immortalized cell lines has been a significant benefit to the study of
human disease, due to limitations in using primary cells and the availability of tissue. The
immortalization of cells from cystic fibrosis (CF) patients as well as cells from non-CF
individuals from tissues relevant to CF has been critical to enhancing our understanding of
the physiological, biochemical and genetic mechanisms underlying CF and for the
development of therapeutic strategies designed to manage CF pathology. A comprehensive …
human disease, due to limitations in using primary cells and the availability of tissue. The
immortalization of cells from cystic fibrosis (CF) patients as well as cells from non-CF
individuals from tissues relevant to CF has been critical to enhancing our understanding of
the physiological, biochemical and genetic mechanisms underlying CF and for the
development of therapeutic strategies designed to manage CF pathology. A comprehensive …
The development of immortalized cell lines has been a significant benefit to the study of human disease, due to limitations in using primary cells and the availability of tissue. The immortalization of cells from cystic fibrosis (CF) patients as well as cells from non-CF individuals from tissues relevant to CF has been critical to enhancing our understanding of the physiological, biochemical and genetic mechanisms underlying CF and for the development of therapeutic strategies designed to manage CF pathology. A comprehensive list of immortalized cells from various tissue and species, with an emphasis on epithelial cells, is presented and discussed here.
Elsevier