Publisher Summary The chapter presents that the primary and metastatic tumor cell growth
results from the development of sophisticated molecular and biological mechanisms that
allow tumor cells to escape immune surveillance. These escape mechanisms are selected
by the cancer cells after a period of interaction with the immune system. Among these
mechanisms, the MHC class I phenotypic alteration that occurs in tumor cells plays a leading
role in the tumor–host scenario since these are crucial molecules for antigen presentation to …