One hundred ninety-one varicella-susceptible children with leukemia in remission were
immunized with live attenuated varicella vaccine. There was serological evidence of an
immune response in approximately 80% after one dose and in more than 90% after two
doses. The major side effect was mild to moderate rash, seen especially in children with
maintenance chemotherapy suspended for one week before and one week after
vaccination. Children with rash had higher antibody titers than those without rash, but those …