[HTML][HTML] Rotenone-induced impairment of mitochondrial electron transport chain confers a selective priming signal for NLRP3 inflammasome activation
Mitochondrial dysfunction is considered crucial for NLRP3 inflammasome activation partly
through its release of mitochondrial toxic products, such as mitochondrial reactive oxygen
species (mROS) 2 2The abbreviations used are: mROSmitochondrial reactive oxygen
speciesmtDNAmitochondrial DNABMDMbone marrow-derived macrophageETCelectron
transport chainMPTmitochondrial permeability transitionCCCPcarbonyl cyanide m-
chlorophenylhydrazoneNACN-acetyl-l-cysteineZ-benzyloxycarbonyl-fmkfluoromethyl …
through its release of mitochondrial toxic products, such as mitochondrial reactive oxygen
species (mROS) 2 2The abbreviations used are: mROSmitochondrial reactive oxygen
speciesmtDNAmitochondrial DNABMDMbone marrow-derived macrophageETCelectron
transport chainMPTmitochondrial permeability transitionCCCPcarbonyl cyanide m-
chlorophenylhydrazoneNACN-acetyl-l-cysteineZ-benzyloxycarbonyl-fmkfluoromethyl …